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3Z has developed unique high throughput zebrafish in vivo screening assays based on behavioural analysis.
These assays have been shown to be effective for screening of neurologically effective drugs and are highly appropriate for drug repurposing.
Zebrafish represent an ideal model for CNS drug screening. They have high genetic similarity to humans, lend themselves to genetic modulation and have a rich repertoire for behavioral phenotyping. Zebrafish express all human neurotransmitters and receptors which makes them ideal for neurological screens.
Using zebrafish offers optimal intersection of human relevance, cost and throughput.