Method

3Z´s method consists of parallel screening of compounds in a sample of ~2500 zebrafish larvae.

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Partners

3Z has partners across a broad area of life sciences and pharmaceutical industry.

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Publications

3Z staff has published a number of scientific papers in academic journals

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Epilepsy assay

3Z Epilepsy assay slide deck is available for download

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Sleep assay

3Z Sleep assay slide deck is now available for download

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3Z – expediting CNS drug discovery

The method developed by 3Z combines the cost efficiency and efficacy of in-vitro tests with the high information content of in vivo testing.

3Z is a preclinical drug company focusing on the discovery of Central Nervous System (CNS) drugs. It provides pharmaceutical companies with expert services in high throughput screening of small molecule libraries for CNS effects.
By automatically monitoring behavior in thousands of zebrafish larvae over 24 hours, using custom built data analysis routines, 3Z can quickly and cost effectively screen thousands of compounds in vivo, significantly reducing the cost and time of CNS drug discovery.

Latest 3Z News

Recently published paper in Behavioral Brain research

3Z´s scientists recently published the paper “Sleep-wake dynamics under extended light and extended dark conditions in adult zebrafish” in Behavioral Brain Research. In this study the effects of light-dark changes on sleep-wake behavior and gene expression in zebrafish were investigated. read more

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Grant from the Icelandic Technology Development Fund

3Z Pharmaceuticals receives a grant from the Icelandic Technology Development fund. The grant (est. 30 million ISK) will be used to perform a high throughput drug screen of a 1200 compound small molecule library, acquired from Prestwick Chemical (France). The screen is aimed at identifying new chemicals that modify sleep and wake behavior. Work on […]

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